Maleic Acid
![Medchemexpress LLC Benzonitrile, 5-[[4-[(6-chlorothieno[2,3-d]pyrimidin-4-yl)amino]-1-piperidinyl]methyl]-2-fluoro- | 866206-54-4 | C19H17ClFN5S | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC Benzonitrile, 5-[[4-[(6-chlorothieno[2,3-d]pyrimidin-4-yl)amino]-1-piperidinyl]methyl]-2-fluoro- | 866206-54-4 | C19H17ClFN5S | 25 MG
PRX-08066 is a selective and orally active 5-hydroxytryptamine receptor 2B (5-HT2BR) antagonist with a Ki of 3.4 nM. It inhibits the MAPK pathway, 5-HT release, and the expression of fibrotic factors. This compound also inhibits the proliferation of KRJ-I cells and induces apoptosis through caspase-3 activation. Additionally, it has been shown to inhibit pulmonary vascular remodeling and is considered for use in pulmonary arterial hypertension (PAH) and neuroendocrine tumors (NET).
- Selective and orally active 5-HT2BR antagonist
- Inhibits MAPK pathway and 5-HT release
- Inhibits expression of fibrotic factors (TGFβ1, CTGF, and FGF2)
- Inhibits proliferation of KRJ-I cells
- Induces apoptosis through caspase-3 activation
- Inhibits pulmonary vascular remodeling
- Potential for use in pulmonary arterial hypertension (PAH)
- Potential for use in neuroendocrine tumors (NET)
Medchemexpress LLC Maleic hydrazide-d2 | 2398483-97-9 | 99.3% | C4H2D2N2O2 | 5 MG
Maleic hydrazide-d2 is a deuterium-labeled form of Maleic hydrazide, a systemic plant growth regulator and herbicide. It inhibits nucleic acid and protein synthesis and can be used as a tracer or internal standard for quantitative analysis in techniques such as NMR, GC-MS, or LC-MS.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration may impact pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Maleic hydrazide | 123-33-1 | 100.0% | C4H4N2O2 | 100 G
Maleic hydrazide is a systemic plant growth regulator and herbicide that functions by inhibiting the synthesis of nucleic acids and proteins. It is used in agriculture, demonstrating lower IC50 values across all tested cell lines compared to Ethephon. It exhibits the least cytotoxicity on Vero cells, followed by Hep2 and HepG2 cells, and shows low acute toxicity through oral, dermal, and inhalation exposure routes.
- Inhibits nucleic acid and protein synthesis
- Low cytotoxicity on Vero, Hep2, and HepG2 cells
- Low acute toxicity via oral, dermal, and inhalation routes
- Systemic plant growth regulator and herbicide
Medchemexpress LLC Prasugrel | 150322-43-3 | MFCD09954140 | C20H20FNO3S | 1 ML
Prasugrel is a thienopyridine and proagent that inhibits platelet function. It is an orally active and potent P2Y12 receptor antagonist, inhibiting ADP-induced platelet aggregation.
- Inhibits platelet function
- Orally active
- Potent P2Y12 receptor antagonist
- Inhibits ADP-induced platelet aggregation
- For research use only
Medchemexpress LLC Maleic hydrazide | 123-33-1 | 99.98% | C4H4N2O2 | 1 ML
Maleic hydrazide (CAS: 123-33-1) is a systemic plant growth regulator and herbicide. It functions as an inhibitor of nucleic acid and protein synthesis, making it useful in agriculture despite its known mutagenic and clastogenic effects. This product is supplied as a 10 mM solution in 1 mL of DMSO, with a purity of 99.98%.
- Acts as a systemic plant growth regulator and herbicide
- Inhibits nucleic acid and protein synthesis
- Exhibits lower IC50 values for cell lines compared to Ethephon
- Shows least cytotoxicity on Vero cells, followed by Hep2 and HepG2 cells
- Has low acute toxicity by oral, dermal, and inhalation routes of exposure
Apexbio Technology LLC Prasugrel hydrochloride 389574-19-0 100mg
Prasugrel hydrochloride (CAS 389574-19-0) is a small molecule inhibitor that targets platelet activation by antagonizing the P2Y12 adenosine diphosphate (ADP) receptor on platelet surfaces By inhibiting this receptor prasugrel impedes ADP-mediated platelet aggregation a critical process in thrombus formation In biochemical assays prasugrel hydrochloride demonstrates an IC50 of 1 8 M for platelet inhibition This compound is utilized in biomedical research to investigate platelet signaling pathways and to model antithrombotic interventions in vitro
Selleck Chemical LLC PRX-08066 Maleic acid
PRX-08066 Maleic acid is a selective 5-HT2B receptor antagonist with IC50 of 3 4 nM prevents the severity of pulmonary arterial hypertension in the MCT rat model Phase 2
Sigma Aldrich Fine Chemicals Biosciences Maleic acid United States300mg
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
eMolecules Ambeed / Maleic acid monoethyl ester / 5g / 600848966 / A850528 / / 3990-03-2 / MFCD00063175 / 144.126 / C6H8O4
Ambeed / Maleic acid monoethyl ester / 5g / 600848966 / A850528 / / 3990-03-2 / MFCD00063175 / 144.126 / C6H8O4
Selleck Chemical LLC Maleic acid S3086-1g
Maleic acid inhibits glutamate decarboxylase (GAD) activity thus enhances acid sensitivity of Listeria monocytogenes Maleic acid affects the extracellular GABA levels
Sigma Aldrich Fine Chemicals Biosciences Maleic acid European Pharmacopoeia (EP) Reference Standard |
Maleic acid European Pharmacopoeia (EP) Reference Standard | Mol Wt: 116.07 |
Selleck Chemical LLC Maleic acid S3086-100mg
Maleic acid inhibits glutamate decarboxylase (GAD) activity thus enhances acid sensitivity of Listeria monocytogenes Maleic acid affects the extracellular GABA levels
Electron Microscopy Sciences Maleic Acid, Crystalline, Repurified, A.C.S. 250 GR
(Toxilic Acid; cis-Butenediodic Acid)
CAS #110-16-7 HOOCCH:CHCOOH F.W. 116.08
Assay: 99.5%
Boiling point: 132-134°C
Sigma Aldrich Fine Chemicals Biosciences Maleic acid ReagentPlusR 925KG
Maleic acid (MA) is a dicarboxylic acid that undergoes esterification with ethanol in the presence of cation-exchange resin catalysts to form diethyl maleate. Its crystalline structure has been analyzed. Reaction kinetics and mechanism of the isomerization of maleic acid to fumaric acid in the presence of ceric and bromide ions has been investigated. The reaction mechanism and reactivity ratios for the radical copolymerization of maleic acid with styrene have been determined.
Medchemexpress LLC Maleic acid | 110-16-7 | MFCD00063177 | >98.0% | 116.07 | C4H4O4 | 5g
Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E coli and L monocytogenes